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What is a normal HCO3 level in ABG?

Published in ABG Interpretation 2 mins read

A normal bicarbonate (HCO3) level in an arterial blood gas (ABG) test is 22 to 26 milliequivalents per liter (mEq/L).

Understanding bicarbonate levels is crucial for assessing a patient's acid-base balance. The ABG test measures the acidity (pH) and the levels of oxygen and carbon dioxide in the blood, along with HCO3.

Normal Bicarbonate (HCO3) Range

Measurement Normal Range Unit
Bicarbonate (HCO3) 22 to 26 mEq/L


This range, as noted in the reference, is generally accepted for adults. Variations can occur based on individual factors and specific lab protocols, so your healthcare provider will interpret your results in the context of your overall health.

What is HCO3?

  • Bicarbonate (HCO3) is a crucial buffer in the blood.
  • It helps maintain the body’s acid-base balance.
  • Kidneys primarily regulate HCO3.
  • It neutralizes acids in the body.

Significance of Abnormal HCO3 Levels

  • High HCO3 levels may indicate metabolic alkalosis, often due to excessive vomiting, diuretics, or excessive bicarbonate intake.
  • Low HCO3 levels can suggest metabolic acidosis, which might be associated with conditions such as kidney failure, diabetic ketoacidosis, or severe diarrhea.

Example Scenarios:

  • Example 1: A patient's ABG shows an HCO3 level of 30 mEq/L. This could suggest metabolic alkalosis.
  • Example 2: A patient’s ABG reveals an HCO3 level of 18 mEq/L. This may indicate metabolic acidosis.

It is essential to note that HCO3 levels should always be evaluated alongside other parameters in an ABG, such as pH and partial pressure of carbon dioxide (PaCO2), to properly assess and diagnose acid-base imbalances. The interpretation of ABG results needs to be done by qualified medical professionals.

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