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How Does Adipose Tissue Grow?

Published in Adipose Tissue Growth 2 mins read

Adipose tissue, commonly known as body fat, grows through different mechanisms depending on the age of the individual.

Growth During Infancy and Adolescence

During the crucial periods of infancy and adolescence, the growth of adipose tissue is characterized by two primary processes:

  • Increase in fat cell size (Hypertrophy): The existing fat cells, also known as adipocytes, expand in size as they accumulate more lipids. This contributes to an increase in overall fat tissue volume, but this is to a lesser extent.
  • Increase in fat cell number (Hyperplasia): More significantly, the number of adipocytes increases during these formative years. This process is the most significant factor contributing to adipose tissue growth. This period is characterized by active cell proliferation, leading to a substantial rise in the number of fat cells, greatly influencing the body's capacity for fat storage later in life.

Growth in Adults

In adulthood, the dynamics of adipose tissue growth shift significantly:

  • Constant Fat Cell Number: In adults, the total number of fat cells remains relatively constant, regardless of moderate weight changes. Even though there is a consistent turnover (about 10% per year), with old cells dying and new cells replacing them, the overall cell number stays consistent when weight is stable.
  • Changes in Fat Cell Size: Weight gain or loss in adults primarily affects the size of existing fat cells, not the number. When adults gain weight, their fat cells become larger as they store more triglycerides (fats). Conversely, when adults lose weight, their fat cells shrink.

Summary

Here's a table summarizing adipose tissue growth in different stages of life:

Stage Primary Growth Mechanism(s) Change in Cell Number Change in Cell Size
Infancy/Adolescence Hyperplasia (major) and Hypertrophy (minor) Increase Increase
Adulthood Hypertrophy Relatively Constant Varies (Increase/Decrease)

Key Takeaway: While fat cells can change size throughout life, particularly in adulthood, the most significant factor influencing the number of fat cells is growth during childhood and adolescence.

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