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What is AGS?

Published in Allergies 2 mins read

AGS, or Alpha-gal syndrome, is an allergic condition where individuals develop an allergy to alpha-gal, a sugar found in most mammals, excluding humans and other primates. It is also referred to as mammalian meat allergy, alpha-gal allergy, red meat allergy, or tick bite meat allergy.

Understanding Alpha-gal Syndrome

Alpha-gal syndrome can be a challenging condition to navigate, impacting dietary choices and requiring vigilance regarding potential exposure.

Key Aspects of AGS:

  • Cause: The allergy is triggered by alpha-gal, a sugar molecule present in most mammalian meat.
  • Trigger: According to provided references, AGS is often associated with tick bites, though the exact mechanism is still under investigation.
  • Symptoms: Symptoms can vary but often include hives, itching, swelling, gastrointestinal distress, and, in severe cases, anaphylaxis after consuming red meat or other mammalian products.
  • Diagnosis: Diagnosis typically involves a blood test to detect antibodies to alpha-gal.
  • Management: Management primarily involves avoiding red meat and other mammalian products. Consultation with an allergist and registered dietitian is crucial for creating a safe and nutritious meal plan.

AGS in a Nutshell:

Aspect Description
Full Name Alpha-gal Syndrome
Other Names Mammalian meat allergy, alpha-gal allergy, red meat allergy, tick bite meat allergy
Cause Allergy to alpha-gal sugar
Source of Alpha-gal Found in the tissues of all mammals except humans and other primates

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