Scientists don't yet fully understand what causes Alzheimer's disease in most people, but the causes likely involve several interconnected factors.
According to current understanding, the development of Alzheimer's disease probably includes a combination of age-related changes in the brain, along with genetic, environmental, and lifestyle factors. These elements are believed to interact in complex ways over time to contribute to the onset and progression of the disease.
Probable Contributing Factors
While research continues to unravel the precise mechanisms, the factors believed to play a role are thought to act together:
- Age-related changes in the brain: As people age, natural changes occur in the brain. Some of these changes may increase vulnerability to Alzheimer's.
- Genetic factors: A person's genetic makeup can influence their risk. Certain genes have been identified that are associated with either a higher or lower likelihood of developing the disease.
- Environmental factors: Elements in the environment may also play a part, although specific factors are still under investigation.
- Lifestyle factors: Individual lifestyle choices and conditions, such as diet, exercise, and cardiovascular health, are also considered potential contributors to Alzheimer's risk.
It's important to understand that it is the combination of these factors, rather than a single cause, that is currently thought to lead to Alzheimer's disease in the majority of cases. The specific mix and impact of these factors can vary from person to person.