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What is amino acid mass?

Published in Amino Acid Chemistry 2 mins read

The mass of an amino acid refers to the weight of a single amino acid molecule. This mass is typically measured in daltons (Da), also known as atomic mass units. Each amino acid has a unique molecular weight due to its specific chemical composition, which includes carbon, hydrogen, oxygen, nitrogen, and sometimes sulfur.

For example, the amino acid glycine has a molecular weight of 57.05 Da, while leucine has a molecular weight of 131.2 Da.

The average molecular weight of an amino acid is approximately 110 Da. This value is often used for estimations, particularly when calculating the molecular weight of proteins.

The molecular weight of an amino acid is essential for various biochemical processes, including:

  • Protein synthesis: The mass of each amino acid determines the overall molecular weight of a protein.
  • Mass spectrometry: This technique uses the mass-to-charge ratio of molecules to identify and quantify them.
  • Amino acid analysis: Determining the amino acid composition of a protein or peptide requires knowledge of the individual amino acid masses.

Here's a table listing some common amino acids and their molecular weights:

Amino Acid Abbreviation Molecular Weight (Da)
Glycine Gly, G 57.05
Alanine Ala, A 71.08
Valine Val, V 99.13
Leucine Leu, L 131.2
Lysine Lys, K 146.2

The precise mass of an amino acid can be calculated based on the atomic weights of its constituent elements. However, for most applications, the average molecular weight is sufficient.

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