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What are amino acids? Why are some of them essential?

Published in Amino Acids 3 mins read

Amino acids are organic compounds that serve as the building blocks of proteins, and some are considered "essential" because the human body cannot synthesize them and they must be obtained from the diet.

What are Amino Acids?

Amino acids are molecules containing an amino group (-NH2), a carboxyl group (-COOH), and a side chain (R group), all attached to a central carbon atom. The R group varies for each amino acid, giving it unique chemical properties. There are 20 standard amino acids used by cells for protein synthesis. Beyond their role in protein construction, amino acids are also precursors to various molecules, including:

  • Hormones: For example, tyrosine is a precursor to thyroid hormones.
  • Neurotransmitters: Examples include glutamate and GABA.
  • Other essential molecules: Such as creatine and heme.

Amino acids are vital for numerous bodily functions, and their presence in adequate quantities is critical for maintaining good health. They're primarily obtained from protein-rich foods like meat, fish, eggs, dairy, legumes, and nuts.

Why are Some Amino Acids Essential?

The classification of amino acids into "essential" and "non-essential" is based on whether the human body can synthesize them.

  • Essential Amino Acids: These amino acids cannot be synthesized by the body in sufficient quantities, or at all, and therefore must be obtained through dietary sources. The nine essential amino acids are:

    • Histidine
    • Isoleucine
    • Leucine
    • Lysine
    • Methionine
    • Phenylalanine
    • Threonine
    • Tryptophan
    • Valine

    A deficiency in one or more essential amino acids can lead to various health problems, including impaired growth, reduced immune function, and digestive issues.

  • Non-Essential Amino Acids: These amino acids can be synthesized by the body from other compounds, so dietary intake is not strictly required. Examples include alanine, asparagine, aspartic acid, and glutamic acid.

  • Conditionally Essential Amino Acids: These amino acids are usually non-essential, but become essential during times of illness, stress, or certain life stages (e.g., infancy). Examples include arginine, cysteine, glutamine, proline, and tyrosine.

In summary, the reason some amino acids are essential lies in our inability to produce them internally. Consuming a balanced diet that includes sufficient protein from various sources is crucial to ensure we get all the essential amino acids needed for optimal health and bodily function.

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