The symptoms of Andersen disease, also known as Glycogen Storage Disease Type IV (GSD IV) or brancher enzyme deficiency, can vary as there are five subtypes. Key symptoms include an enlarged liver, cirrhosis, and failure to thrive. Secondary symptoms can also include cardiac failure and muscle issues.
Here's a breakdown:
- Enlarged Liver: This is a common initial finding.
- Cirrhosis: Scarring of the liver can occur, leading to impaired liver function.
- Failure to Thrive: Infants may not gain weight or grow at the expected rate.
- Cardiac Failure: The heart may weaken and struggle to pump blood effectively.
- Muscle Issues: Problems with muscle function can arise.
| Symptom | Description |
|---|---|
| Enlarged Liver | Liver becomes larger than normal. |
| Cirrhosis | Scarring of the liver, impacting its function. |
| Failure to Thrive | In infants, inadequate weight gain and growth. |
| Cardiac Failure | The heart's inability to pump enough blood to meet the body's needs. |
| Muscle Issues | Problems with muscle strength, function, or coordination. |
