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What Antibiotics Treat Colitis?

Published in Antibiotic Treatment 2 mins read

The following antibiotics are used to treat colitis, as referenced in the provided information:

Antibiotic Treatments for Colitis

Colitis, inflammation of the colon, can sometimes be treated with antibiotics depending on the cause. Here are the specific antibiotics and dosages:

Oral Antibiotics:

  • Ciprofloxacin: 500mg (12.5mg/kg) taken orally every 12 hours for 3 days.
  • Norfloxacin: 400mg (10mg/kg) taken orally every 12 hours for 3 days.
  • Azithromycin: 500mg (10mg/kg) taken orally daily for 3 days. This antibiotic is used when quinolone resistance is suspected (e.g., in areas like South and East Asia).

Intravenous Antibiotics:

  • Ceftriaxone: 2g (50mg/kg) administered intravenously daily for 3 days, used when oral administration is not possible.

Specific Considerations:

  • Quinolone Resistance: If there is a suspicion of resistance to quinolone antibiotics (like ciprofloxacin or norfloxacin), particularly in regions like South and East Asia, azithromycin is preferred.
  • Oral vs. IV: The preferred route is oral administration whenever feasible. Ceftriaxone via intravenous route is reserved for situations where oral medications cannot be used.
  • Duration: All the above-mentioned treatments are typically administered for 3 days.
Antibiotic Dosage Route Frequency Duration Notes
Ciprofloxacin 500mg (12.5mg/kg) Oral Every 12 hrs 3 days
Norfloxacin 400mg (10mg/kg) Oral Every 12 hrs 3 days
Azithromycin 500mg (10mg/kg) Oral Daily 3 days Use if quinolone resistance suspected (eg S & E Asia)
Ceftriaxone 2g (50mg/kg) IV Daily 3 days Use if oral administration is not feasible

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