Antibiotics that treat Carbapenemase-Producing Enterobacterales (CPE) infections include novel beta-lactam/beta-lactamase inhibitor combinations and, in some cases, meropenem/vaborbactam.
Treatment Options for CPE Infections
When treating invasive CPE infections, susceptibility testing is crucial to guide antibiotic selection. Here's a breakdown of antibiotic options based on the reference provided:
- Novel beta-lactam/beta-lactamase inhibitor combination therapies: These can be used alone (monotherapy) or in combination with other antibiotics.
- Meropenem/vaborbactam: This combination is specifically recommended for invasive infections caused by Klebsiella pneumoniae carbapenemase (KPC)-producing resistant Enterobacterales.
