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Can Cefixime Be Used for Skin Infections?

Published in Antibiotic Use 2 mins read

Yes, cefixime can be used to treat certain skin infections.

Cefixime is a broad-spectrum antibiotic belonging to the cephalosporin class. Cephalosporins are beta-lactam antibiotics effective against various bacterial infections, including those affecting the skin. As mentioned in the reference, cefixime, being a third-generation cephalosporin, can be used to treat skin infections caused by susceptible gram-positive and gram-negative bacteria.

How Cefixime Works Against Skin Infections

Cefixime works by inhibiting the formation of the bacterial cell wall, which is essential for bacterial survival. This action leads to bacterial cell death, effectively combating the infection.

Key Points About Cefixime and Skin Infections:

  • Broad-Spectrum Antibiotic: Cefixime is effective against a wide range of bacteria, making it useful for various skin infections.
  • Third-Generation Cephalosporin: This classification indicates its spectrum of activity and is related to its effectiveness against many types of bacteria.
  • Orally Active: Cefixime is administered orally, which is convenient for treating skin infections that do not require intravenous administration.

Considerations When Using Cefixime for Skin Infections

While cefixime can be effective, it's crucial to consult a healthcare professional for accurate diagnosis and treatment. Factors to consider include:

  • Type of Infection: Not all skin infections respond to cefixime. The specific bacteria causing the infection must be susceptible to this antibiotic.
  • Resistance: Overuse of antibiotics can lead to resistance, so cefixime should be used only when necessary and as prescribed.
  • Allergies: People with known allergies to cephalosporins or penicillins should avoid cefixime.
  • Side Effects: As with all antibiotics, cefixime may have potential side effects. Discuss these with a healthcare provider.


In summary, cefixime is a viable option for treating certain skin infections caused by susceptible bacteria. However, it should only be used under the guidance of a healthcare professional.

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