Whether an AST level of 200 IU/L is considered high depends on the normal reference range used by the specific laboratory performing the test. However, based on one reference, an AST level of 200 IU/L could be within the typical range, even in some cases of severe disease.
Here's a breakdown:
- Reference Range Consideration: Normal AST ranges can vary between labs. Always refer to the specific range provided with your test results.
- Disease Severity: According to the provided reference, "The AST is typically in the 100 to 200 IU/L range, even in severe disease." This suggests that 200 IU/L, while potentially upper-end, might not automatically indicate a significantly high level, even when liver damage exists.
- Other Factors: Isolated AST levels should be interpreted with caution. Doctors usually look at the Alanine Aminotransferase (ALT) and the AST/ALT ratio, among other tests, to assess liver health more comprehensively. For example, the reference notes, "The AST level is higher than the ALT level, and the ratio is greater than 2:1 in 70% of patients," which is suggestive of alcoholic hepatitis if the ratio is greater than 3.