Based on the provided reference, "pure disease" most likely refers to Pure Autonomic Failure (PAF).
Understanding Pure Autonomic Failure (PAF)
PAF, also known as Bradbury-Eggleston syndrome or idiopathic orthostatic hypotension, is a neurodegenerative disease affecting the autonomic nervous system. This system controls involuntary bodily functions like heart rate, blood pressure, and digestion. Specifically, PAF impacts the sympathetic branch of the autonomic nervous system.
Key Characteristics of PAF:
- Orthostatic Hypotension: The primary symptom of PAF is a significant drop in blood pressure upon standing. This can lead to dizziness, lightheadedness, fainting, or other related issues.
- Neurodegenerative: PAF is a progressive condition, meaning it can worsen over time.
- Autonomic Nervous System Dysfunction: The disease exclusively targets the automatic functions of the body and doesn’t affect conscious movement or senses.
PAF vs. Other Forms of Autonomic Dysfunction
It's important to note that PAF is different from other conditions that cause autonomic dysfunction. While other neurological disorders can also affect the autonomic nervous system, they may also present other symptoms not exclusive to automatic dysfunction. Pure Autonomic Failure is characterized by being a specific disease focused on this part of the nervous system.
Summary in Table Form
| Feature | Description |
|---|---|
| Disease Name | Pure Autonomic Failure (PAF), also known as Bradbury-Eggleston syndrome or idiopathic orthostatic hypotension |
| Type | Neurodegenerative |
| Target | Sympathetic branch of the autonomic nervous system |
| Primary Symptom | Orthostatic Hypotension |
| Other Names | Bradbury-Eggleston syndrome, Idiopathic orthostatic hypotension |
In conclusion, while other diseases can cause autonomic dysfunction, the term "pure disease" in this context, most likely refers to Pure Autonomic Failure (PAF) which is characterized by primary dysfunction of the autonomic nervous system, specifically the sympathetic branch leading to orthostatic hypotension.
