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How do bacterial spores grow?

Published in Bacterial Spore Germination 2 mins read

Bacterial spores do not "grow" in the typical sense. They germinate to become vegetative cells when conditions are favorable. The spore is a dormant, highly resistant structure formed as a response to adverse conditions by a vegetative cell.

Here's a breakdown of the process:

  1. Spore Formation (Sporulation): When environmental conditions become unfavorable (e.g., nutrient depletion, extreme temperatures), a vegetative bacterial cell initiates sporulation. According to the provided reference, a vegetative cell is the cell that produces the spore. This is a survival mechanism.

  2. Dormancy: The spore is metabolically inactive and highly resistant to heat, radiation, chemicals, and desiccation. It can remain in this dormant state for extended periods.

  3. Germination: When favorable conditions return, the spore undergoes germination. This is not growth; it's a transformation back into a vegetative cell.

  4. Outgrowth: After germination, the new vegetative cell begins to grow and divide, resuming normal bacterial life. Each spore germinates into only one vegetative cell, as indicated by the reference.

Feature Spore Vegetative Cell
Metabolic State Dormant, inactive Active
Resistance Highly resistant to harsh conditions Susceptible to harsh conditions
Function Survival Growth and reproduction
Formation Formed in response to adverse conditions Arises from spore germination or division
Cell per Spore One vegetative cell makes one spore One spore makes one vegetative cell

Therefore, bacterial spores don't grow; they transform back into a growing (vegetative) state under suitable conditions.

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