Behçet's disease is called "Silk Road disease" because it is more prevalent in populations along the ancient Silk Road trade route.
Prevalence Along the Silk Road
The disease is characterized by a higher occurrence in people of Mediterranean, Middle Eastern, and Far Eastern descent. These regions historically formed the core of the Silk Road, a network of trade routes connecting the East and West for centuries. Turkey and Japan have particularly high rates of Behçet's disease.
Geographical Distribution as a Clue
The geographical distribution of Behçet's disease suggests a possible environmental or genetic factor linked to populations that historically migrated or traded along the Silk Road. While the exact cause of Behçet's disease is unknown, researchers believe it's a combination of genetic predisposition and environmental triggers. The "Silk Road disease" moniker highlights this intriguing epidemiological pattern.
