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What class is metformin?

Published in Biguanide 2 mins read

Metformin belongs to a class of medications known as biguanides. This drug is widely used to manage blood glucose levels in individuals, primarily those with type 2 diabetes.

Understanding Metformin's Drug Class: Biguanides

Biguanides are a group of oral antidiabetic drugs that work by lowering glucose production by the liver. Metformin is the only biguanide currently available and approved for use in many countries. It has been a cornerstone of diabetes management for decades due to its effectiveness and well-understood mechanism of action.

Below is a quick overview of Metformin's classification and primary functions:

Drug Name Class Primary Function(s)
Metformin Biguanide Controls blood glucose levels; Decreases glucose absorption from food; Decreases glucose made by the liver

How Metformin Works to Control Blood Sugar

As a biguanide, metformin operates through several key mechanisms to help regulate blood glucose (sugar) levels. Based on its well-established pharmacological profile, its primary actions include:

  • Decreasing Hepatic Glucose Production: Metformin significantly reduces the amount of glucose produced by the liver. This is a crucial action as the liver naturally releases glucose, and in individuals with insulin resistance, this production can be excessive.
  • Reducing Intestinal Glucose Absorption: It lowers the amount of glucose absorbed into the bloodstream from the food you consume. This means less sugar from your diet enters your system rapidly after meals.
  • Improving Insulin Sensitivity: While not directly mentioned in the provided reference, it's a known mechanism that metformin enhances the body's response to insulin, allowing cells to take up more glucose from the blood.

By performing these actions, metformin effectively helps to control the amount of glucose circulating in your blood, making it a vital medication for diabetes management.

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