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What is the last stage of bilirubin?

Published in Bilirubin Metabolism 1 min read

The last stage of bilirubin involves its processing in the intestine. Conjugated bilirubin is converted by bacteria into mesobilirubinogen and urobilinogen.

Here's a breakdown of the process:

  • Initial Stage: Conjugated bilirubin enters the intestine from the gallbladder or liver.
  • Bacterial Action: Bacteria in the intestine transform conjugated bilirubin.
  • Intermediate Products: The bacteria convert it to mesobilirubinogen and urobilinogen.
  • Final Steps:
    • Some urobilinogen is reabsorbed into the blood.
    • The remaining urobilinogen is either returned to the liver or excreted in urine and feces (Reference: 31-Jul-2024).

Therefore, the end products in the breakdown of bilirubin are urobilinogen and mesobilirubinogen, which are then either reabsorbed, processed further, or excreted.

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