Yes, zinc can lower bilirubin levels. Studies indicate that both chronic and acute use of zinc salts can reduce serum bilirubin levels. This happens because zinc inhibits the enterohepatic cycle of indirect bilirubin [11].
How Does Zinc Lower Bilirubin?
Zinc works by:
- Inhibiting the Enterohepatic Cycle: By interfering with this cycle, zinc prevents bilirubin from being reabsorbed back into the bloodstream.
- Increasing Bilirubin Excretion: Oral administration of zinc sulfate has been shown to increase the excretion of bilirubin, leading to a decrease in its serum level [3, 12].
Studies and Evidence
The effectiveness of zinc in lowering bilirubin is supported by research:
Study Focus | Findings |
---|---|
Chronic and Acute Zinc Salt Use | Reduces serum bilirubin levels by inhibiting the enterohepatic cycle of indirect bilirubin |
Oral Administration of Zinc Sulfate | Increases bilirubin excretion and decreases its serum level |
References
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