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Is DNA positive or negative?

Published in Biochemistry 1 min read

DNA is negatively charged. This is due to the presence of phosphate groups in the nucleotides that make up the DNA molecule. The phosphate backbone of DNA has a net negative charge because of the bonds formed between phosphorus and oxygen atoms.

This negative charge is important for several reasons, including:

  • DNA packaging: The negative charge of DNA attracts positively charged proteins called histones, which help to compact and organize DNA into chromosomes within the nucleus of a cell.
  • DNA replication: During DNA replication, the negative charge of DNA helps to attract and hold the enzymes that are responsible for copying the DNA molecule.
  • DNA transcription: The negative charge of DNA also plays a role in transcription, the process of copying DNA into RNA.

The negative charge of DNA is a fundamental property that is essential for its function.

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