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Is FAD a protein?

Published in Biochemistry 2 mins read

No, FAD (flavin adenine dinucleotide) is not a protein. It is a coenzyme.

What is FAD?

FAD is a crucial redox-active coenzyme involved in a wide array of enzymatic reactions within metabolism. It is typically associated with various proteins, acting as a helper molecule to facilitate their function.

FAD vs. Flavoproteins

While FAD itself is not a protein, it often works in conjunction with proteins. A protein that contains either FAD or flavin mononucleotide (FMN) is called a flavoprotein. The flavoprotein is the protein, and the FAD (or FMN) is the flavin group bound to it. This flavin group is essential for the protein's enzymatic activity.

Key Differences Summarized

Feature FAD Flavoprotein
Definition Redox-active coenzyme Protein containing FAD or FMN
Function Facilitates enzyme reactions Catalyzes specific reactions
Composition Adenine, ribose, phosphate, flavin Amino acids + FAD/FMN
Example Part of succinate dehydrogenase Succinate dehydrogenase itself

In essence, FAD is a component that assists certain proteins (flavoproteins) in carrying out their enzymatic duties. It is akin to a tool that a carpenter (the protein) uses to build something; the tool is not the carpenter itself.

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