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What is NADPH used for?

Published in Biochemistry 2 mins read

NADPH is primarily used in biosynthesis reactions, acting as a reducing agent. Specifically, according to the provided reference, NADPH serves crucial roles in several metabolic pathways.

NADPH's Key Uses

NADPH (Nicotinamide adenine dinucleotide phosphate) is an essential reducing agent in various biochemical reactions. Its uses can be summarized as follows:

  • Biosynthesis: NADPH is vital for the production of several essential molecules within the body. This includes:

    • Lipids:
      • Fatty acids: Building blocks of cell membranes and energy storage.
      • Cholesterol: Important for cell membrane structure and hormone synthesis.
    • Neurotransmitters: Chemicals that transmit signals between nerve cells.
    • Nucleotides: Building blocks of DNA and RNA.
    • Amino acids: Building blocks of proteins.
  • Photosynthesis: In plants, NADPH plays a dual role:

    • Electron acceptor in the light-dependent reactions.
    • Electron donor in the light-independent reactions (Calvin cycle), where it helps convert carbon dioxide into glucose.

Summary Table of NADPH Uses

Use Description Example
Biosynthesis Production of essential molecules Synthesis of fatty acids, cholesterol, nucleotides
Photosynthesis Electron transfer in light-dependent and light-independent reactions Carbon fixation in the Calvin cycle

In essence, NADPH provides the necessary reducing power for anabolic reactions, allowing organisms to build complex molecules from simpler ones.

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