The isoelectric point (pI) of leucine is 6.04.
The isoelectric point (pI) is the pH at which a molecule carries no net electrical charge. For amino acids like leucine, which have an amino group and a carboxyl group, the pI is the average of the pKa values of these two groups. The side chain of leucine is non-ionizable, which simplifies the pI calculation. Leucine is an aliphatic nonpolar amino acid.
| Amino Acid | Abbreviation | pI (25° C) |
|---|---|---|
| Leucine | Leu | 6.04 |
