ATP (adenosine triphosphate) and AMP (adenosine monophosphate) are related because AMP is a product of ATP after it has been hydrolyzed to release energy. ATP essentially loses two phosphate groups to become AMP.
Here's a breakdown of their relationship:
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ATP (Adenosine Triphosphate): This molecule is the primary energy currency of cells. It consists of an adenosine molecule bonded to three phosphate groups. These phosphate groups are linked by high-energy bonds.
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Hydrolysis: When a cell needs energy, ATP undergoes hydrolysis. This process involves breaking one or two of the phosphate bonds.
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ADP (Adenosine Diphosphate): Breaking one phosphate bond yields ADP (adenosine diphosphate) and releases energy.
ATP + H₂O → ADP + Pi + Energy
where Pi represents inorganic phosphate.
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AMP (Adenosine Monophosphate): Breaking two phosphate bonds (either directly from ATP or sequentially from ATP to ADP to AMP) yields AMP (adenosine monophosphate) and releases energy.
ATP + H₂O → AMP + PPi + Energy
where PPi represents pyrophosphate (two phosphate groups bonded together). The pyrophosphate can then be further hydrolyzed into two inorganic phosphates: PPi + H2O → 2Pi
Or, sequentially:
ATP + H₂O → ADP + Pi + Energy ADP + H₂O → AMP + Pi + Energy
In essence, AMP is what remains of ATP after it has donated two of its phosphate groups to provide energy for cellular processes. AMP can be recycled back into ATP through the addition of phosphate groups, requiring energy input. Think of ATP as a fully charged battery, ADP as a partially discharged battery, and AMP as a significantly discharged battery. The cell's energy production processes recharge these "batteries."