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What is CLL disease?

Published in Blood Cancer 2 mins read

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow.

Understanding CLL

CLL is characterized by the bone marrow producing too many lymphocytes. Lymphocytes are a type of white blood cell that are crucial for the immune system. In CLL, these cells become abnormal and multiply uncontrollably, crowding out healthy blood cells.

Key Features of CLL

  • Slow Progression: CLL typically progresses slowly, often over many years.
  • Blood and Bone Marrow Cancer: It primarily affects the blood and bone marrow.
  • Abnormal Lymphocytes: The disease involves the overproduction of abnormal lymphocytes.

Disease Progression

The uncontrolled production of these abnormal lymphocytes leads to a range of issues, including:

  • Crowding of healthy cells: This can result in anemia (low red blood cell count), thrombocytopenia (low platelet count), and an increased risk of infections.
  • Lymph node enlargement: Swollen lymph nodes can occur as the abnormal lymphocytes accumulate.
  • Organ involvement: In advanced stages, CLL can affect other organs such as the spleen and liver.

In summary

CLL is a blood and bone marrow cancer where too many abnormal lymphocytes are produced in the bone marrow. It generally gets worse slowly over time.

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