ADP (adenosine 5′-diphosphate) plays a role in enhancing thrombus formation, but its role in initiating coagulation has not yet been revealed.
While ADP's exact role in initiating coagulation remains unclear, it is known to be important in the process of blood clotting through platelet aggregation and thrombus formation. The primary role of ADP in blood clotting is to enhance thrombus formation. It achieves this by:
- Recruiting platelets: ADP attracts more platelets to the site of injury, increasing the density of the platelet plug.
- Recruiting leukocytes: ADP also recruits leukocytes (white blood cells) to the area.
- Enhancing platelet adhesion: ADP helps platelets adhere to the collagen exposed at the injury site, forming the initial layer of the clot.
In summary, according to research from 2004, the adenosine 5′-diphosphate (ADP) pathway is known to enhance thrombus formation by recruiting platelets and leukocytes to the primary layer of collagen-adhering platelets, its role for the initiation of coagulation has not been revealed.
