askvity

What is the Difference Between Plasma and Plasma Protein?

Published in Blood Components 3 mins read

The fundamental difference is that plasma is the liquid component of blood, and plasma proteins are substances dissolved within that plasma. Think of plasma as the solvent and the proteins as solutes.

Plasma is the straw-colored, liquid matrix of blood. It makes up a significant portion of blood volume. According to the reference, plasma is primarily composed of:

  • Water: 91% to 92%
  • Solids: 8% to 9%

These solids include a variety of dissolved substances essential for bodily functions.

What is Plasma?

Plasma is a vital component of blood that carries cells like red blood cells, white blood cells, and platelets throughout the body. Beyond transporting cells, plasma itself transports numerous dissolved substances, including:

  • Nutrients (glucose, amino acids)
  • Waste products (urea, creatinine)
  • Hormones
  • Electrolytes (sodium, potassium)
  • Coagulants (like fibrinogen)
  • And crucially, plasma proteins.

Essentially, plasma is the transportation medium for blood cells and many other molecules in the circulatory system.

What are Plasma Proteins?

Plasma proteins are a major category of the solids dissolved in plasma. They are large, complex protein molecules produced mainly by the liver. As stated in the reference, plasma contains plasma proteins, such as albumin and globulin.

These proteins perform numerous critical functions:

  • Maintain Colloidal Osmotic Pressure: As highlighted in the reference, plasma proteins, particularly albumin, are essential for maintaining the colloidal osmotic pressure at about 25 mmHg. This pressure helps draw water back into the capillaries from the tissues, preventing excessive fluid loss from the bloodstream and avoiding swelling.
  • Transport Substances: Proteins like albumin bind to and transport various molecules, including hormones, fatty acids, and drugs.
  • Immunity: Globulins include antibodies (immunoglobulins) that are crucial for the immune response.
  • Blood Clotting: Fibrinogen is a plasma protein that is a key component in the blood clotting process.

Key Differences Summarized

Here’s a simple table illustrating the distinction:

Feature Plasma Plasma Protein
Type Liquid component of blood Specific type of molecule dissolved in plasma
Composition Primarily water, containing solids A category of solids within plasma (e.g., albumin)
Relationship Contains plasma proteins Is a component of plasma
Function Transport medium, carries substances Specific roles like maintaining osmotic pressure, transport, immunity

In short, plasma is the liquid vehicle, and plasma proteins are important passengers with specific jobs within that vehicle.

Related Articles