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Which Disease is Caused by an Increase of Platelets?

Published in Blood Disorder 2 mins read

An increase in platelet count, also known as thrombocytosis, can be a symptom of several diseases. The most directly related is thrombocythemia.

Understanding Thrombocythemia and Related Conditions

Thrombocythemia, often called essential thrombocythemia (ET), is a disease where the bone marrow produces too many platelets. This overproduction can lead to blood clots or excessive bleeding. Symptoms can include blood clots, bruising, bloody stools, and weakness. [Source: Multiple sources including the provided text on Thrombocythemia]

However, it's crucial to understand that a high platelet count (thrombocytosis) isn't always a disease itself but can be secondary or reactive to other underlying conditions. This means another illness or condition triggers the increased platelet production.

Several conditions can cause reactive thrombocytosis:

  • Infections: Various infections can stimulate the bone marrow to produce more platelets.
  • Chronic Inflammatory Diseases: Conditions like autoimmune diseases contribute to elevated platelet counts.
  • Cancer: Certain cancers can also lead to increased platelet production.
  • Anemia: Iron deficiency, among other anemias, is associated with high platelet counts.
  • Medications: Some medications can cause a rise in platelet levels.

It's important to note that diagnosing the cause of thrombocytosis is crucial because treating the underlying condition is usually the key to managing the high platelet count. Simply treating the high platelet count without addressing the root cause is unlikely to be successful. [Source: Multiple sources, including snippets mentioning secondary thrombocytosis, causes of high platelet count, and the importance of underlying conditions]

Therefore, while thrombocythemia is a disease characterized by an increased platelet count, a high platelet count is frequently a symptom of various other medical conditions.

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