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What Causes High Hemoglobin?

Published in Blood Disorders 2 mins read

High hemoglobin levels, indicating an unusually high amount of the protein that carries oxygen in red blood cells, are most often caused by low blood oxygen levels (hypoxia) sustained over a long period. This prompts the bone marrow to increase red blood cell production to compensate.

Several factors can lead to this chronic low oxygen:

Common Causes of High Hemoglobin

  • Chronic Lung Diseases: Conditions like chronic obstructive pulmonary disease (COPD), emphysema, and cystic fibrosis impair oxygen uptake, triggering increased hemoglobin production.
  • Heart Conditions: Heart failure and congenital heart defects reduce the blood's ability to carry oxygen efficiently, causing the body to boost hemoglobin levels.
  • High Altitude Living: The lower oxygen levels at high altitudes stimulate the body to produce more red blood cells.
  • Smoking: Smoking damages the lungs, reducing oxygen absorption and leading to higher hemoglobin levels.
  • Dehydration: Concentrated blood from dehydration can falsely elevate hemoglobin levels.
  • Bone Marrow Disorders: Polycythemia vera, a bone marrow disease, causes an abnormal increase in red blood cell production, resulting in elevated hemoglobin.
  • Kidney Cancer and Liver Cancer: Certain cancers can lead to increased erythropoietin production, a hormone that stimulates red blood cell formation, ultimately raising hemoglobin levels.

Less Common Causes

While less frequent, other conditions can contribute to elevated hemoglobin:

  • Congenital heart disease in adults.

It's crucial to note that high hemoglobin doesn't always cause symptoms. However, high levels can lead to complications like blood clots. A healthcare professional will need to perform a thorough evaluation to determine the underlying cause of increased hemoglobin and provide appropriate treatment.

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