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Why is MCHC High?

Published in Blood Health 3 mins read

High Mean Corpuscular Hemoglobin Concentration (MCHC) indicates that red blood cells have a higher-than-normal concentration of hemoglobin within them. According to the provided reference, an MCHC value above 36 g/dL is considered high. This increase can stem from various underlying medical conditions.

Understanding MCHC

MCHC measures the average concentration of hemoglobin inside a red blood cell. Hemoglobin is the protein in red blood cells that carries oxygen. When MCHC is high, it means there’s a greater amount of hemoglobin packed into each cell.

Causes of High MCHC

Several health issues can lead to elevated MCHC levels:

  • Some types of anemia: Certain forms of anemia, not all, can cause MCHC to rise.
  • Liver disease: Problems with the liver can affect red blood cell production and hemoglobin concentration.
  • Overactive thyroid: An overactive thyroid (hyperthyroidism) can disrupt various bodily processes, including blood cell production, potentially leading to high MCHC.

These conditions lead to variations in symptoms and health outcomes. For example:

  • Anemia may present with fatigue, weakness, and pale skin.
  • Liver disease might cause jaundice (yellowing of the skin and eyes), abdominal pain, and swelling.
  • Hyperthyroidism can result in weight loss, rapid heartbeat, and anxiety.

Diagnosing High MCHC

Diagnosis of the underlying causes involves:

  1. Blood tests: Repeated complete blood count (CBC) to confirm MCHC levels.
  2. Additional tests: Tests for specific anemias, liver function, and thyroid hormone levels may be performed.
  3. Medical history and physical exam: Doctors review patient's history and conduct an exam to look for specific symptoms related to the possible causes.

Table of MCHC and associated conditions

Condition Potential Symptoms Impact on MCHC
Some types of Anemia Fatigue, weakness, pale skin Increase
Liver Disease Jaundice, abdominal pain, swelling Increase
Overactive Thyroid Weight loss, rapid heartbeat, anxiety Increase

What to do if your MCHC is high

If your blood test indicates high MCHC, follow these steps:

  • Consult your doctor: It is crucial to discuss your results with your doctor.
  • Undergo further testing: Your doctor might order additional tests.
  • Follow treatment plans: If diagnosed with a specific condition, adhere to the recommended treatment plan.

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