Both C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are blood tests used to detect inflammation in the body. However, they measure different aspects of inflammation, leading to distinct interpretations.
- CRP directly measures the levels of a specific protein produced by the liver in response to inflammation. It is a sensitive and rapid indicator of acute inflammation.
- ESR, on the other hand, is an indirect measure of inflammation. It measures the rate at which red blood cells settle at the bottom of a test tube. This rate is influenced by various factors, including fibrinogen, which increases during inflammation. ESR is more helpful in monitoring chronic inflammatory conditions.
In summary:
- CRP is a more direct and sensitive marker for acute inflammation, while ESR is a less sensitive but more helpful indicator for chronic inflammation.