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Can a cousin be a bone marrow match?

Published in Bone Marrow Donation 2 mins read

It's highly unlikely, but possible, for a cousin to be a bone marrow match.

While siblings are the most likely relatives to be a close match, extended family members like cousins have a significantly lower chance. This is because bone marrow matching depends on Human Leukocyte Antigens (HLA), which are inherited. The more distant the relationship, the less HLA genes are shared.

Here's a breakdown:

  • Siblings: Have a 25% chance of being a perfect match (if both parents are the same).
  • Parents: Have a 50% chance of sharing one HLA haplotype, but are unlikely to be a complete match.
  • Cousins: Have a very low chance of being a match, as the shared genetic material decreases with each generation removed.

While the odds are slim, a cousin could be a match if they happen to inherit a similar HLA type. It's important to register with a bone marrow registry to explore all possible matches, including unrelated donors.

What if a cousin isn't a match?

Even if a cousin isn't a perfect bone marrow match, they can still help in other ways:

  • Joining the registry: Encouraging cousins and other family members to join the bone marrow registry expands the pool of potential donors for all patients in need.
  • Fundraising and awareness: Supporting organizations that facilitate bone marrow donations can help more people find matches.

In conclusion, while a cousin matching is rare, it is not impossible. Always prioritize searching the bone marrow registry first.

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