The injection directly into the bone marrow is known as Intra–bone marrow injection.
Understanding Intra–Bone Marrow Injection
Intra–bone marrow injection is a medical procedure where substances are injected directly into the spongy tissue inside the bone, which is the bone marrow. This route is often used for specific therapies, particularly those involving cells.
Applications, According to Reference
According to the reference "Stem cell transplantation. Intra–bone marrow injection of bone marrow and cord blood cells: an alternative way of transplantation associated with a higher seeding efficiency", this type of injection is utilized in the field of stem cell transplantation.
- Delivery Method: It serves as an "alternative way of transplantation" for delivering cells, specifically:
- Bone marrow cells
- Cord blood cells
- Potential Benefit: The reference highlights that this method is "associated with a higher seeding efficiency" compared to other routes, suggesting that more of the transplanted cells may successfully engraft or settle in the bone marrow.
Why Inject into the Bone Marrow?
Injecting directly into the bone marrow allows therapies, particularly cellular therapies like stem cell transplants, to be delivered precisely to the site where they are intended to function or engraft. This direct delivery can potentially improve the effectiveness of the treatment.
While intravenous (into a vein) injection is a common method for cell delivery in transplantation, the intra–bone marrow route places the cells directly within the bone marrow environment, which is crucial for their survival and differentiation.
