The largest bone in the skull is actually made up of two bones: the right and left parietal bones. These bones are connected by the sagittal suture and together form the largest bone in the skull. The second largest bone is the frontal bone.
The mandible, also known as the jawbone, is often mistaken for the largest bone in the skull. While it is the strongest and largest bone in the face, it is not the largest bone in the entire skull.
The femur is the largest bone in the human body overall, located in the thigh. The humerus, the bone in the upper arm, is the largest bone in the upper extremity.