Leukoaraiosis refers to specific abnormalities observed in brain scans, particularly in older individuals.
Understanding Leukoaraiosis
Leukoaraiosis is a descriptive term used in neuroimaging to describe changes in the brain's white matter. Specifically, it appears as areas that are either less dense (hypodense) or more dense (hyperintense) than normal white matter on imaging scans like CT or MRI [1, 2].
Key Characteristics
- Location: These abnormalities are frequently found around the ventricles (periventricular area) of the brain [1, 2].
- Appearance: They appear as lighter or darker patches compared to the normal white matter on brain scans.
- Prevalence: Leukoaraiosis is more commonly seen in older adults [1, 2].
Significance of Leukoaraiosis
While leukoaraiosis is often observed with increasing age, it can also be associated with various conditions, including:
- Vascular disease: High blood pressure and other conditions affecting blood vessels.
- Cognitive impairment: May be linked to decline in thinking and memory skills.
- Dementia: Increased risk of developing dementia.
Summary
In summary, leukoaraiosis represents changes in the white matter of the brain seen on neuroimaging, most often found in the elderly and in the periventricular area. These findings are linked to aging and vascular disease, and can be associated with cognitive impairment.