The cause of RMS disease depends on what RMS refers to. RMS can stand for either Rhabdomyosarcoma or Relapsing-Remitting Multiple Sclerosis. Therefore, the causes differ significantly.
Rhabdomyosarcoma (RMS)
The exact cause of rhabdomyosarcoma (a type of cancer) is unknown. While researchers understand that changes in a cell's DNA are involved in cancer development, the specific triggers for these changes in RMS remain largely unclear. [16-Jul-2018 Reference] There are very few known risk factors, but some genetic syndromes increase the risk:
- Li-Fraumeni syndrome
- Beckwith-Wiedemann syndrome
- Neurofibromatosis
- Costello syndrome
- Cardiofaciocutaneous syndrome [My.Cleveland Clinic Reference]
Relapsing-Remitting Multiple Sclerosis (RMS)
Relapsing-remitting multiple sclerosis (RMS) is a progressive disease damaging the central nervous system (CNS). The precise cause is unknown, but scientists believe it's likely a combination of genetic predisposition and environmental triggers. An infection is suspected as a potential contributing factor. [Johns Hopkins Medicine Reference]
In summary, the cause of "RMS disease" is dependent on the specific condition being referred to. For rhabdomyosarcoma, the cause is unknown but linked to DNA changes; for relapsing-remitting multiple sclerosis, it's thought to be a complex interplay of genetics and environmental factors, possibly including infection.
