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What are the 40,000 cells in the heart?

Published in Cardiac Neuroscience 2 mins read

The 40,000 cells in the heart are sensory neurites, also known as neurons. These neurons form the heart's intrinsic cardiac nervous system, often referred to as the heart's "little brain."

The Heart's "Little Brain": A Network of Neurons

The heart isn't just a pump; it possesses its own complex nervous system. This system, containing approximately 40,000 sensory neurites (Armour, 1991), plays a crucial role in various functions:

  • Communication with the Brain: These neurites send information about the heart's state, including sensory information like pressure and stretch, to the brain via afferent pathways. This constant communication contributes to the body's overall regulation and awareness.
  • Memory Transfer: Research suggests a potential role for these cells in memory transfer (https://pmc.ncbi.nlm.nih.gov/articles/PMC10896837/). While this area needs further study, the implication is that the heart's intrinsic nervous system might contribute to emotional and even cognitive processes.

Research and Discoveries

The existence of this extensive neural network within the heart was a significant discovery. Research dating back to the early 1990s revealed the presence of these neurons, which are similar in type to those in the brain (https://research.jefferson.edu/2022-magazine/the-hearts-little-brain.). Further studies continue to map these cells using advanced techniques like 3-D microscopy, improving our understanding of their intricate connections and functions (https://www.sciencenews.org/article/new-3-d-map-illuminates-little-brain-nerve-cells-within-heart).

Key Takeaways:

  • The heart contains approximately 40,000 sensory neurites.
  • These neurites constitute the heart's intrinsic nervous system, a complex network crucial for communication with the brain.
  • Ongoing research continues to reveal the full extent of the heart's neural network and its impact on overall health and well-being.

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