Yes, RBCs (Red Blood Cells) do have cytoplasm.
The cytoplasm of red blood cells is a critical component, primarily filled with hemoglobin. Hemoglobin is the protein responsible for binding and transporting oxygen and carbon dioxide throughout the body. The high concentration of hemoglobin within the cytoplasm gives erythrocytes their characteristic intense red color when stained with eosin in histological preparations like Hematoxylin and Eosin (H&E) stained tissue samples.
Essentially, while RBCs lack a nucleus and other typical organelles found in most cells when mature, their cytoplasm is present and functionally vital for their oxygen-carrying role. It's this hemoglobin-rich cytoplasm that allows RBCs to perform their primary function.
