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What are goblet cells?

Published in Cell Biology 2 mins read

Goblet cells are specialized epithelial cells found in the lining of the digestive and respiratory tracts. They are named for their goblet-like shape, which is due to the large amount of mucin stored within their cytoplasm.

Goblet cells play a vital role in maintaining the health of these surfaces by secreting mucus, a thick, sticky substance that acts as a protective barrier. This mucus helps to:

  • Lubricate the surface: Mucus allows food to move smoothly through the digestive tract and prevents friction in the respiratory system.
  • Trap foreign particles: In the respiratory system, mucus traps dust, pollen, and other irritants, preventing them from entering the lungs.
  • Protect the lining: The mucus layer provides a physical barrier, preventing harmful microbes from adhering to and damaging the delicate tissues underneath.
  • Facilitate immune responses: Goblet cells are involved in regulating immune responses at mucosal surfaces, including the recruitment of immune cells to fight infections.

Goblet cells are found in different locations within the digestive and respiratory systems, and the specific type of mucin they produce can vary depending on their location. For example, goblet cells in the intestines produce a different type of mucin than those in the respiratory system.

In summary, goblet cells are essential for maintaining the health of our digestive and respiratory systems. They secrete mucus, which acts as a lubricant, trap foreign particles, protects the lining, and plays a role in immune responses.

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