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What is the difference between the cell cycle and mitosis?

Published in Cell Biology 3 mins read

The cell cycle is the entire life cycle of a cell, while mitosis is just one specific phase within that cycle, focused on nuclear division.

Here's a more detailed breakdown:

The Cell Cycle: A Complete Life

The cell cycle represents the complete sequence of events from one cell division to the next. It's a continuous process involving growth, DNA replication, and cell division. Think of it as the overall lifecycle.

  • Purpose: Growth and reproduction of cells.
  • Phases:
    • Interphase: The longest phase, where the cell grows, replicates its DNA, and prepares for division. It consists of G1, S, and G2 phases.
      • G1 Phase (Gap 1): Cell growth and normal metabolic functions.
      • S Phase (Synthesis): DNA replication occurs.
      • G2 Phase (Gap 2): Further growth and preparation for mitosis.
    • M Phase (Mitotic Phase): The phase where the cell divides its nucleus (mitosis) and cytoplasm (cytokinesis).

Mitosis: Nuclear Division

Mitosis is a specific part of the cell cycle, specifically the division of the nucleus resulting in two identical daughter nuclei.

  • Purpose: To accurately separate duplicated chromosomes, ensuring each daughter cell receives a complete and identical set of genetic material.
  • Phases:
    • Prophase: Chromosomes condense and become visible.
    • Prometaphase: The nuclear envelope breaks down and spindle fibers attach to the chromosomes.
    • Metaphase: Chromosomes align at the middle of the cell.
    • Anaphase: Sister chromatids separate and move to opposite poles of the cell.
    • Telophase: The nuclear envelope reforms around each set of chromosomes.
  • Cytokinesis: Although technically separate from mitosis, it usually overlaps with telophase. Cytokinesis is the division of the cytoplasm, resulting in two separate daughter cells.

Key Differences Summarized

Feature Cell Cycle Mitosis
Definition The entire lifecycle of a cell. Nuclear division; a phase within the cell cycle.
Scope Broad: Includes growth, DNA replication, and division. Narrow: Specifically focuses on chromosome separation.
Result Prepares and results in two new cells. Divides the nucleus into two identical nuclei.

In essence, mitosis is a critical, visually distinct part of the larger process of the cell cycle. The cell cycle encompasses all the steps necessary for a cell to duplicate itself, while mitosis is the specific process of dividing the nucleus containing the genetic material.

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