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What diseases cause cell death?

Published in Cell Death Diseases 2 mins read

Many diseases can cause cell death, leading to various health issues. Some common examples include:

  • Neurodegenerative diseases:
    • Alzheimer's disease: Characterized by the formation of amyloid plaques and neurofibrillary tangles, leading to the death of brain cells and cognitive decline.
    • Huntington's disease: A genetic disorder affecting the nervous system, causing the death of neurons in the basal ganglia, resulting in involuntary movements and cognitive impairment.
    • Parkinson's disease: Involves the loss of dopamine-producing neurons in the substantia nigra, leading to tremors, rigidity, and slow movements.
  • Blood disorders:
    • Aplastic anemia: A rare condition in which the bone marrow fails to produce enough blood cells, including red blood cells, white blood cells, and platelets, leading to cell death and potential organ damage.
  • Cardiovascular diseases:
    • Heart attack: Occurs when the blood supply to a part of the heart is interrupted, causing damage and death of heart muscle cells.
    • Stroke: Happens when a blood vessel in the brain bursts or becomes blocked, cutting off blood flow and oxygen to the brain, resulting in neuronal death.
  • Autoimmune diseases:
    • Multiple sclerosis (MS): An autoimmune disease where the immune system attacks the myelin sheath protecting nerve fibers, leading to inflammation and damage, eventually causing nerve cell death.
  • Diabetes:
    • Type I diabetes: An autoimmune disease where the immune system attacks the insulin-producing cells in the pancreas, leading to cell death and impaired glucose regulation.

These are just a few examples of diseases that cause cell death. It's essential to remember that various factors can contribute to cell death, including genetics, environment, lifestyle, and other diseases.

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