Radiation primarily kills cells through two distinct pathways, with the most immediate being apoptosis, also called programmed cell death or interphase death.
Cell Death Mechanisms Due to Radiation
Here's a breakdown of how radiation causes cell death:
Apoptosis (Programmed Cell Death)
- Immediate Response: Apoptosis, or programmed cell death, is a rapid response to radiation damage. Cells that are damaged beyond repair initiate this self-destruct process.
- Interphase Death: Cells undergoing apoptosis as a direct consequence of radiation die within hours of exposure, without needing to go through cell division (mitosis). This is also known as "interphase death" because it occurs during the cell's resting phase.
- Timing: This process typically occurs within a few hours of irradiation, indicating a direct and quick cellular response to the damage caused by radiation.
| Mechanism | Description | Timing |
|---|---|---|
| Apoptosis/Interphase Death | Programmed self-destruction of damaged cells after radiation exposure | Within a few hours |
Key Takeaway
- Radiation-induced cell death can occur rapidly through apoptosis. This programmed cell death occurs without the need for the cell to undergo division, usually taking place within hours of exposure to radiation.
