Skin cell death can be referred to by several terms depending on the specific process involved.
- Cornification: This is a specialized form of programmed cell death that occurs in keratinocytes, the main cells in the epidermis. It leads to the formation of a tough, protective layer on the skin.
- Apoptosis: This is a process of programmed cell death that is essential for normal development and tissue homeostasis. It is a controlled process that eliminates unwanted or damaged cells without causing inflammation.
- Necrosis: This is an uncontrolled form of cell death that occurs due to injury or disease. It is characterized by cell swelling, rupture, and release of cellular contents, which can cause inflammation.
- Ferroptosis: This is a form of cell death characterized by iron-dependent lipid peroxidation. It is linked to various diseases, including cancer and neurodegenerative disorders.
Skin cells can also die due to other factors, such as UV radiation damage, which can trigger a process called ribotoxic stress.
