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What is n in mitosis?

Published in Cell Division Genetics 2 mins read

In the context of mitosis, 'n' represents the number of complete sets of chromosomes within a cell.

Understanding 'n' and 'c' in the Cell Cycle

To fully grasp the meaning of 'n', it's helpful to distinguish it from 'c', which represents the DNA content in a cell. According to the provided reference, these are distinct measures that change throughout the cell cycle.

Term Definition
n Number of complete sets of chromosomes
c DNA content in a cell

Mitosis and Chromosome Sets

Mitosis is a type of cell division that results in two daughter cells, each having the same number and kind of chromosomes as the parent nucleus. This is how the 'n' value is maintained. Here is an example for diploid cells:

  • Starting Point: A diploid cell, commonly represented as 2n, has two complete sets of chromosomes (one set from each parent).
  • During Mitosis: The cell duplicates its DNA, temporarily increasing its 'c' value, but the number of chromosome sets ('n') remains the same.
  • End of Mitosis: The cell divides into two identical daughter cells, each containing a 2n configuration, so the number of complete chromosome sets stays constant during this process.

Practical Insights

  • In most human cells, 'n' equals 2 (2n), meaning there are two sets of chromosomes.
  • During mitosis, while DNA is duplicated, 'n' does not change in the daughter cells.
  • 'n' is critical in understanding the ploidy of a cell and the genetic makeup.

In Conclusion

'n' represents the number of complete sets of chromosomes within a cell, a key factor in understanding the genetic state during mitosis and the cell cycle. The process of mitosis ensures the 'n' value remains the same as the parent cell in each of the daughter cells.

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