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What is the difference between cytokinesis and telophase?

Published in Cell Division 3 mins read

Cytokinesis and telophase are both crucial phases in cell division, but telophase precedes cytokinesis; telophase completes nuclear division, while cytokinesis divides the cytoplasm, resulting in two distinct daughter cells.

Telophase: Rebuilding the Nucleus

Telophase is the final stage of mitosis or meiosis I & II, focusing on the reformation of the nucleus. Key events include:

  • Chromosome Arrival: Sister chromatids (in mitosis) or homologous chromosomes (in meiosis I) arrive at opposite poles of the cell.
  • Nuclear Envelope Reformation: A new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei.
  • Chromosome Decondensation: The chromosomes begin to unwind and decondense, returning to their more diffuse chromatin state.
  • Spindle Disassembly: The mitotic spindle, responsible for chromosome segregation, disassembles.

Essentially, telophase reverses many of the events of prophase and prometaphase, preparing the cell for the physical separation of its contents.

Cytokinesis: Dividing the Cytoplasm

Cytokinesis follows telophase and is the process where the cytoplasm of the cell divides, physically separating the two newly formed nuclei into two distinct daughter cells. The mechanism differs between animal and plant cells:

  • Animal Cells: Cytokinesis occurs through the formation of a cleavage furrow. A contractile ring of actin filaments forms at the cell's equator and progressively constricts, pinching the cell in two.
  • Plant Cells: Due to the presence of a rigid cell wall, plant cells undergo cytokinesis by forming a cell plate. Vesicles containing cell wall material fuse at the cell's equator, gradually forming a new cell wall that separates the two daughter cells.

Key Differences Summarized

The following table highlights the core differences between telophase and cytokinesis:

Feature Telophase Cytokinesis
Main Event Reformation of the nucleus Division of the cytoplasm
Timing Final stage of mitosis/meiosis I & II Occurs after telophase
Key Structures Nuclear envelope, chromosomes, spindle Cleavage furrow (animal cells), cell plate (plant cells)
Outcome Two nuclei in one cell Two separate daughter cells

In simple terms, telophase sets the stage, and cytokinesis carries out the final act of physically separating the cell into two. Without both processes, cell division would be incomplete.

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