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Where are Desmosomes?

Published in Cell Junctions 2 mins read

Desmosomes, which are strong cell-to-cell adhesion structures, are found in tissues that experience significant mechanical stress.

Tissues Containing Desmosomes

Here's a breakdown of where you'll typically find desmosomes, as indicated by the provided reference:

Tissue Type Description
Cardiac Muscle Tissue Found in the heart muscle, ensuring that the cells remain connected during contractions.
Bladder Tissue Present in the bladder wall, where they help maintain tissue integrity as the bladder expands and contracts.
Gastrointestinal Mucosa Located in the lining of the digestive tract, where they resist mechanical forces during digestion.
Epithelia Found in various epithelial tissues, contributing to the structural stability and integrity of these cell layers.

Significance of Desmosomes

  • Desmosomes provide robust connections between cells.
  • They are essential in areas where mechanical stress is high.
  • Their presence ensures the structural integrity of tissues.
  • They play an important role in preventing tissue damage under mechanical pressure.

Examples

  • Heart: In cardiac muscle, desmosomes allow the heart muscle to function without cells separating during each heart beat.
  • Skin: Desmosomes help hold the skin together, so it can resist tearing and other physical stresses.
  • Digestive System: Desmosomes play a critical role in the gastrointestinal tract, helping the tissues withstand movement and the abrasive nature of digestion.
  • Bladder: Desmosomes help bladder tissue withstand expansion and contraction of the bladder.

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