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What is a KB cell?

Published in Cell Lines 2 mins read

A KB cell is an adherent epithelial cell line initially believed to be derived from an epidermal carcinoma of the mouth.

In more detail:

  • Cell Type: KB cells are a type of cultured human cell.

  • Origin: They were initially thought to originate from an epidermal carcinoma, which is a type of cancer, found in the mouth. While the specific origin is debated, they serve as a valuable model in cellular research.

  • Characteristics: KB cells are adherent, meaning they grow attached to a surface, unlike suspension cells which float freely in a culture medium. They also exhibit epithelial characteristics, similar to cells that line the surfaces of the body.

  • Applications: KB cells are used in a variety of research applications, including:

    • Drug testing.
    • Studying cellular mechanisms.
    • Cancer research.
  • Example: Researchers might use KB cells to test the effectiveness of a new chemotherapy drug on a type of mouth cancer cell. The results can help inform treatment strategies.

In summary, a KB cell is an adherent epithelial cell line initially believed to be derived from a mouth epidermal carcinoma, widely utilized for in vitro research.

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