The β (Beta) adrenergic receptors increase cAMP levels.
Beta-Adrenergic Receptors and cAMP
Beta-adrenergic receptors are a class of G protein-coupled receptors that are activated by catecholamines, such as norepinephrine and epinephrine. When a hormone binds to a beta-adrenergic receptor, it triggers a cascade of events that ultimately leads to an increase in the intracellular concentration of cyclic adenosine monophosphate (cAMP).
- Mechanism: The activated receptor stimulates adenylyl cyclase, an enzyme that catalyzes the conversion of ATP to cAMP.
- Result: The increased cAMP then acts as a second messenger, activating protein kinase A (PKA), which phosphorylates various intracellular proteins, leading to diverse physiological effects.
Summary Table
| Receptor | Effect on cAMP Levels | Mechanism |
|---|---|---|
| β (Beta) adrenergic receptors | Increases | Activates adenylyl cyclase, which converts ATP to cAMP. |
