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How do neurons exist?

Published in Cellular Biology 3 mins read

Neurons come into existence as the direct result of cell division. Specifically, they are daughter cells formed after the final division of pre-neuron cells. Here's a breakdown of the process:

Neuron Development: From Pre-Neuron to Functional Cell

The journey of a neuron from its origin is complex. It's not just about creating a new cell, but also about shaping its identity and function. The process can be understood as follows:

1. The Pre-Neuron Stage

  • These precursor cells undergo a series of divisions, eventually leading to the cells that will become neurons or glial cells.

2. Final Division and Daughter Cell Creation

  • The final division of a pre-neuron cell results in daughter cells. This is when the critical decision is made: will this cell become a neuron, or a supporting glial cell?

3. Epigenetic Influences on Cell Fate

  • The fate of each daughter cell—whether it becomes a neuron or a glial cell, and even what type of neuron it becomes—is decided by its epigenetic circumstances. Epigenetics refers to changes in gene expression that do not involve changes to the underlying DNA sequence.
  • These epigenetic factors include:
    • Chemical modifications to DNA.
    • Histone modifications affecting how DNA is packed.
    • Non-coding RNAs which regulate gene expression.
    • Environmental signals surrounding the cell.

4. Neuron Type Specialization

  • If a daughter cell is fated to be a neuron, it still has more decisions to make. The nervous system contains hundreds of types of neurons. Epigenetic factors dictate the specific subtype of neuron a cell will become. This influences its connections, function, and overall role in the brain.

Summary of Neuron Existence

Aspect Description
Origin Daughter cells of the final division of pre-neuron cells.
Cell Fate Determination Epigenetic circumstances decide if the cell becomes a neuron or glial cell, and which type of neuron it is.
Key Influences Chemical modifications, histone modifications, non-coding RNAs, and environmental signals.
Neuron Diversity Hundreds of types of neurons exist, each with specific functions, which are also determined by epigenetic factors.

In summary, neurons exist as the direct result of cell division, where their developmental path is dictated by epigenetic signals that decide their nature and function in the nervous system.

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