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Is Keratin a Dead Cell?

Published in Cellular Biology 2 mins read

No, keratin itself is not a dead cell, but keratin is a protein, and the keratin found in certain structures like hair is produced by dead cells. Specifically, the keratin in the hair shaft comes from dead keratinocytes.

The Role of Keratinocytes

  • Living Cells: Keratinocytes are living cells found in the skin and hair follicles.
  • Keratin Production: They are responsible for producing keratin, a tough, fibrous protein.
  • Cornification: As keratinocytes mature, they undergo a process called cornification. During this process, the cells become filled with keratin and ultimately die.

Hair and Keratin

  • Hair Shaft: The visible part of the hair, the hair shaft, is primarily composed of dead keratinocytes packed with keratin.
  • From Hair Bulb: According to the reference, the hair shaft's keratin comes from keratinocytes that originated in the hair bulb. These cells undergo cornification, and the result is the hardened keratin that makes up our hair.

Other Structures with Keratin

While the hair is formed from dead cells, keratin is also found in other structures, such as skin and nails. These structures also contain keratin, but the keratinocytes in these areas undergo constant replacement.


Feature Description
Keratin A protein; a structural component of skin, hair, and nails.
Keratinocytes Living cells that produce keratin; they undergo cornification (death and hardening).
Hair Shaft Made of dead keratinocytes filled with keratin.
Cornification Process where keratinocytes fill with keratin and die, forming the tough structure.


In summary, while the keratin protein is not a cell, the keratin found in hair is a result of dead keratinocytes that have undergone cornification.

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