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Understanding Zombie Cells

Published in Cellular Biology 2 mins read

Are Zombie Cells Alive?

Yes, zombie cells, also known as senescent cells, are still alive. However, they are dysfunctional. They've stopped dividing and performing their normal functions, yet they persist in the body. This is why they are referred to as "zombie" cells—they are alive but not functioning properly.

  • Definition: Senescent cells are damaged cells that have stopped dividing but haven't died. [Source: Med.umn.edu, Cedars-Sinai]
  • Function: Unlike healthy cells, they don't contribute to tissue repair or renewal. [Source: UPMC]
  • Harmful Effects: They release harmful chemicals that damage surrounding healthy cells and contribute to inflammation. [Source: Mayo Clinic News Network, Med.umn.edu]
  • Accumulation: The number of senescent cells increases with age, potentially contributing to age-related diseases. [ScienceAlert]

Several studies highlight the characteristics and implications of these cells:

  • A study in Cell Metabolism explored ways to target these specific cells to improve lifespan and health in mice. [Source: Medscape]
  • Researchers are actively working to identify and map these cells within the body. [Source: UT Health Science Center San Antonio]
  • Scientists have identified proteins secreted by these cells that can serve as biomarkers, predicting health outcomes in older adults. [Source: Mayo Clinic News Network]

While the term "zombie cells" is a metaphor, it accurately reflects their state: alive but effectively dead in terms of normal cellular function. The continued existence of these cells and their secretion of harmful substances is a significant area of research in the study of aging and age-related diseases. [Source: Wake Forest University]

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