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What is the difference between lysosomes and mesosomes?

Published in Cellular Biology 2 mins read

Lysosomes and mesosomes are both cellular structures, but they differ significantly in their function, origin, and the type of cells in which they are found. Lysosomes are found in eukaryotic cells (cells with a nucleus), while mesosomes are found in prokaryotic cells (cells without a nucleus).

Lysosomes

  • Definition: Lysosomes are membrane-bound cell organelles that contain digestive enzymes.
  • Function: According to the reference, lysosomes play a crucial role in cellular digestion. They contain various hydrolyzing digestive enzymes that break down waste materials and cellular debris. They also protect cells from pathogens by hydrolyzing them with their enzymes.
  • Cell Type: Eukaryotic cells (e.g., animal and plant cells).
  • Origin: Formed from the Golgi apparatus.
  • Analogy: Think of lysosomes as the "recycling centers" of the cell.

Mesosomes

  • Definition: Mesosomes are invaginations or inward folds of the cell membrane in prokaryotic cells.
  • Function: The reference states that mesosomes are inward folds in the cell membranes of prokaryotic cells. While their exact function has been debated, they were initially thought to play roles in DNA replication, cell division, and respiration. However, it's now believed that mesosomes might be artifacts of the chemical fixation process used during electron microscopy. Therefore their existence in vivo is under question.
  • Cell Type: Prokaryotic cells (e.g., bacteria).
  • Origin: Infoldings of the plasma membrane.
  • Analogy: Though their role is debated, they were thought to potentially function like a primitive version of eukaryotic organelles (mitochondria, etc.).

Summary Table: Lysosomes vs. Mesosomes

Feature Lysosomes Mesosomes
Cell Type Eukaryotic Prokaryotic
Primary Function Cellular Digestion, Defense against pathogens Originally thought: DNA replication, respiration. Now mainly considered as artifacts
Origin Golgi Apparatus Infoldings of the plasma membrane
Composition Digestive enzymes Cell membrane

In essence, lysosomes are organelles responsible for breaking down and recycling cellular material in eukaryotic cells, while mesosomes are infoldings of the cell membrane in prokaryotic cells whose existence in vivo is under question and whose functions are still debated.

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